How does dr do nitration with cpap or what is nitration?
Saturday, June 5th, 2010 at
10:39 am
I have been diagnosed with obstructive sleep apnea a month ago, was for sleep studies, got a temporary tracheostomy and septum plasty, now in this week has to go for nitration and cpap machine. what do they mean with nitration?
Filed under: Obstructive Sleep Apnea
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Obstructive sleep apnea comprises episodes of partial and/or complete closure of the upper airway during sleep leading to breathing cessation, defined as > 10 sec. Symptoms include restlessness, snoring, recurrent awakening, morning headache, and excessive daytime sleepiness. Diagnosis is based on sleep history, physical examination, and polysomnography. Treatment is with nasal continuous positive airway pressure, oral appliances, and, in refractory cases, surgery. Prognosis is good with treatment, but most cases are undiagnosed and untreated, resulting in hypertension, heart failure, and injury and death from motor vehicle and other accidents resulting from hypersomnolence.
Long-term intermittent hypoxia increases nitration and oxidation in many brain regions including those involved in sleep/wake control. A major source of longterm intermittent hypoxia -induced nitration appears to be inducible nitric oxide synthase (iNOS):
CPAP means Continuous Positive Airway Pressure.
Please see the web pages on CPAP and Google search on Nitration with CPAP.
I think you mean TITRATION of your CPAP machine -
Basically, you go in overnight, and wear your CPAP machine. Remember CPAP stands for Continuous Positive Airway Pressure – its a mask that you wear that delivers air into your airway using pressure. This is different from a simple nasal cannula or oxygen mask, which passively delivers oxygen.
Anyway, overnight, you’re going to wear your CPAP machine, and the technicians/doctor will monitor your blood oxygen saturation continuously (via a probe on your finger or ear). They will slowly increase the pressure that your CPAP machine delivers – trying to get the best oxygen delivery to your lungs, while still allowing you to be comfortable while sleeping.
The pressure the CPAP is delivered is measured in centimeters of water (cmH20). Once they determine the best pressure – they will set your machine for you, tell you how many cmH20 you’re at, and send you home. You may need to come back one more time for a similar experience.
Also, as time goes on, you may require more or less cmH20 – and that will be titrated as needed. Hope this helps – good luck!